The synthesis of 4-benzylamino-6-methyl-1H-pyrrolo[3,2-c]pyridine and 4-benzylamino-6-methyl-1H-pyrrolo[2,3-b]pyridine was written by Meade, Eric A.;Beauchamp, Lilia M.. And the article was included in Journal of Heterocyclic Chemistry in 1996.Category: pyridine-derivatives This article mentions the following:
Deaza analogs of 2-methyl-N-(phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, i.e., 6-methyl-N-(phenylmethyl)-1H-pyrrolo[3,2-c]pyridin-4-amine (I) and 6-methyl-N-(phenylmethyl)-1H-pyrrolo[2,3-b]pyridin-4-amine (II) were prepared The 1-deaza analog I was prepared via a multi-step procedure from a pyrrole precursor, 1-benzyl-2-formylpyrrole, while the 3-deaza analog II was synthesized from 2-amino-3,6-dimethylpyridine. I and II were found to be devoid of anxiolytic activity. In the experiment, the researchers used many compounds, for example, 3,6-Dimethyl-2-pyridinamine (cas: 823-61-0Category: pyridine-derivatives).
3,6-Dimethyl-2-pyridinamine (cas: 823-61-0) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Category: pyridine-derivatives