Insights into Substrate Self-Assisted Activation of Allylic Alcohols Guiding to Mild Allylic Substitution of Tautomerizable Heteroarenes was written by Zhou, Qiuju;Zheng, Lingyun;Ma, Bing;Huang, Lijun;Liu, Aoqi;Cao, Xinhua;Yu, Jing;Ma, Xiantao. And the article was included in Journal of Organic Chemistry in 2020.Safety of Pyridin-4-ol This article mentions the following:
A substrate self-assisted activation of allylic alcs. by tautomerizable heteroarenes via hydrogen bonding was disclosed by various NMR techniques, including variable-temperature 1H NMR, Job plot, and 1H NMR titration Guided by these finding, a much milder allylic substitution of tautomerizable heteroarenes with allylic alcs. was developed, affording the target products in high yields. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Safety of Pyridin-4-ol).
Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Safety of Pyridin-4-ol