Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Quality Control of 5-Bromo-2-fluoropyridine, 766-11-0, Name is 5-Bromo-2-fluoropyridine, molecular formula is C5H3BrFN, belongs to pyridine-derivatives compound. In a document, author is Hu, Chen-Chen, introduce the new discover.
2-Position-selective C-H fluoromethylation of six-membered heteroaryl N-oxides with (fluoromethyl)triphenylphosphonium iodide
A mild and efficient method for the regioselective C-H fluoromethylation of heteroaryl N-oxides with (fluoromethyl)triphenylphosphonium iodide is presented. With LiOt-Bu as the base and HMSO as the solvent, this reaction delivers a series of C2-fluommethylated pyridine and quinoline derivatives in moderate to good yields. This protocol also extends the synthetic applications of (fluommethyl)triphenylphosphonium iodide.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 766-11-0. Quality Control of 5-Bromo-2-fluoropyridine.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem