Mn(II) tags for DEER distance measurements in proteins via C-S attachment was written by Martorana, Andrea;Yang, Yin;Zhao, Yu;Li, Qing-Feng;Su, Xun-Cheng;Goldfarb, Daniella. And the article was included in Dalton Transactions in 2015.Category: pyridine-derivatives This article mentions the following:
Mn2+ chelating tags for Mn2+-Mn2+ distance measurements by pulse EPR spectroscopy were developed. They feature a stable C-S conjugation to the protein, high reactivity towards cysteine thiols and short and rigid linkers that can be used in distance measurements with high resolution under reductive conditions. Double electron-electron resonance measurements at 95 GHz on ubiquitin labeled with these tags showed the expected narrow distance distribution. In the experiment, the researchers used many compounds, for example, (4-Bromopyridin-2-yl)methanol (cas: 131747-45-0Category: pyridine-derivatives).
(4-Bromopyridin-2-yl)methanol (cas: 131747-45-0) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Category: pyridine-derivatives