Electrolytic C-H Oxygenation via Oxidatively Induced Reductive Elimination in Rh Catalysis was written by Jin, Seongho;Kim, Jinwoo;Kim, Dongwook;Park, Jung-Woo;Chang, Sukbok. And the article was included in ACS Catalysis in 2021.Application In Synthesis of 2-(m-Tolyl)pyridine This article mentions the following:
Herein, the development of a Rh-catalyzed C-H acyloxylation under mild electrolytic conditions is described. Anodic oxidation of a key rhodacyclic carboxylate intermediate was found to enable the product-releasing C-O bond-forming reductive elimination process. An accumulation of carboxylate near the electrode surface was rationalized to further induce the desired C-O bond formation, allowing an ambient catalytic C-H oxygenation using stoichiometric amounts of readily accessible carboxylic acid coupling partners. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Application In Synthesis of 2-(m-Tolyl)pyridine).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six 锜?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H鐪塩kel criteria for aromatic systems. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Application In Synthesis of 2-(m-Tolyl)pyridine