Decker oxidation of 2-substituted N-alkylpyridinium compounds. Part 5. Decker oxidation of homarine was written by Weber, Horst. And the article was included in Archiv der Pharmazie (Weinheim, Germany) in 1976.SDS of cas: 59864-31-2 This article mentions the following:
The Decker oxidation of homarine (I) gave 85% 1-methyl-2-pyridone. Oxidation of I using K3[Fe(CN)6] in 30% NaOH gave 82% II (R = OH). Also prepared were II (R = OEt, NH2, NHMe, NHPh, NHCH2Ph, NEt2, NHNH2, NHNHPh) in 73-95% yields from the reactions of II (R = Cl) with the resp. nucleophiles. In the experiment, the researchers used many compounds, for example, 1-Methyl-6-oxo-1,6-dihydropyridine-2-carboxylic acid (cas: 59864-31-2SDS of cas: 59864-31-2).
1-Methyl-6-oxo-1,6-dihydropyridine-2-carboxylic acid (cas: 59864-31-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. SDS of cas: 59864-31-2