Let¡¯s face it, organic chemistry can seem difficult to learn, SDS of cas: 5431-44-7, Especially from a beginner¡¯s point of view. Like 5431-44-7, Name is 2,6-Pyridinedicarboxaldehyde, molecular formula is pyridine-derivatives, belongs to pyridine-derivatives compound. In a document, author is Wang Xiang, introducing its new discovery.
One-Pot Three-Component Synthesis of 3-(1H-Benzo[d]imidazol-2-yl)chromen Derivatives
Benzoimidazole and chromen derivatives exhibit a variety of important biological activities. Chromens incorporating benzoimidazole moiety have high Rho kinase inhibitory activity. However, the effective synthetic method for the preparation of these compounds is rare. The efficient synthesis of new substituted 3-(1H-benzo[d]imidazol-2-yl)-4H- chromens in 48%similar to 89% yields via one-pot, three-component reaction of 2-(1H-benzo[d]imidazol-2-yl)acetonitrile with aromatic aldehydes and 5,5-dimethylcyclohexane-1,3-dione was studied. This reaction was carried out in EtOH in the presence of pyridine under reflux conditions. All reactions were completed within 1 to 3 h.
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem