Chemistry is an experimental science, Formula: C17H15NO3, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 4803-74-1, Name is 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one, molecular formula is C17H15NO3, belongs to pyridine-derivatives compound. In a document, author is Koca, Basak.
Organocatalysts in Ring-Opening Polymerization: Revealing Their Effect on Stereochemistry
Organocatalysts derived from thioureas and amines commonly play a part in ring-opening polymerization (ROP) of lactone monomers such as 8-valerolactone and mandelic o-carboxyanydride. Organocatalysts have a dual role in ROP reactions they create a balance between the rate and the selectivity; the fate of the reaction depends on their structure, the presence of the co-initiator and the degree of basicity. These parameters eventually determine the stereochemistry of the final product which is highly associated with the activation mechanism of the monomer. Thereupon, we performed a computational study to understand the course of action of several organocatalysts combined with co-initiators having different basicities and we have thus shed light on the tacticity of the products by using density functional theory (DFT). Calculations have shown that electron withdrawing CF3 groups on the benzene ring significantly ensure the selectivity through hydrogen bonding, while the balance between nucleophilicity and basicity of pyridine determines the reaction pathway. We have also demonstrated that bifunctional organocatalysts can be tuned to increase the isotactic yield in the ROP reaction of mandelic o-carboxyanydride.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 4803-74-1, in my other articles. Formula: C17H15NO3.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem