Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 1945-84-2, Name is 2-Ethynylpyridine, molecular formula is C7H5N. In an article, author is Yakovenko, Georgiy G.,once mentioned of 1945-84-2, COA of Formula: C7H5N.
A convenient synthesis method of 5-oxopyrazolo[4,3-b]pyridine-6-carboxylic acids and their nitriles
N-Boc-protected 5-formyl-1H-pyrazol-4-amines react with malonic acid in pyridine in the presence of pyrrolidine at 45-50 degrees C or with malonic acid monomethyl ether in the presence of pyrrolidine in AcOH under reflux with the formation of 5-oxo-4,5-dihydro-1Hpyrazolo[4,3-b]pyridine-6-carboxylic acids. The reaction of N-Boc-protected 5-formyl-1H-pyrazol-4-amines with cyanoacetic acid in pyridine in the presence of pyrrolidine at 45-50 degrees C leads to the formation of 5-oxo-4,5-dihydro-1H-pyrazolo[4,3-b]pyridine-6-carbonitriles. The latter can also be obtained via cyclocondensation of N-Boc-protected 5-formyl-1H-pyrazol-4-amines with methyl cyanoacetate in AcOH under reflux in the presence of pyrrolidine or in MeCN containing pyrrolidine and a catalytic amount of proline heated under reflux.
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem