Electric Literature of 51173-04-7, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 51173-04-7, Name is 5-Fluoro-2-methoxypyridine, SMILES is COC1=NC=C(F)C=C1, belongs to pyridine-derivatives compound. In a article, author is Shokoohian, Maryam, introduce new discover of the category.
Pseudo-three-component synthesis of substituted 1,2,4-triazolo[1,5-a]pyridines
Heterocyclic 1,2,4-triazoles and their derivatives, such as triazolopyridines, have been used as leading components for the synthesis of numerous heterocyclic compounds; and because of their various biological activities, they have a distinct location in pharmaceutical and medicinal chemistry. In this article, we demonstrate a new way of synthesizing 1,2,4-triazolo[1,5-a]pyridine derivatives, as a one-pot pseudo-three-component reaction, via the reaction of pyridine-2-(1H)-one derivatives and 1,4-cyclohexadione in the adjacency of acetic acid both as solvent and an inexpensive and green catalyst at 50 degrees C. The desired products were synthesized in good yields, and the chemical structure of the synthesized compounds was recognized using H-1 and C-13 NMR spectra, FT-IR, melting point, mass spectroscopy, and elementary analysis. [GRAPHICS] .
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem