Reference of 24057-28-1, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 24057-28-1, Name is Pyridin-1-ium 4-methylbenzenesulfonate, SMILES is CC1=CC=C(S(=O)([O-])=O)C=C1.C2=CC=CC=[NH+]2, belongs to pyridine-derivatives compound. In a article, author is Kohout, Victoria R., introduce new discover of the category.
Automated solution-phase syntheses of alpha 1 -> 2, 1 -> 3 type rhamnans and rhamnan sulfate fragments
Rhamnan and rhamnan sulfate are naturally occurring carbohydrates that have important biological functions and possible therapeutic applications, but studies are limited to the microheterogeneous mixtures from natural sources. This work reports the first synthesis of any sulfated rhamnan fragments and successful automation of the process with a recently developed automated solution-phase approach using N-iodosuccinimide/trimethylsilyl triflate (NIS/TMSOTf) promotor and levulinoyl ester deprotection conditions. The automated solution-phase activation/deprotection approach was initially able to create alpha 1 -> 2, 1 -> 3 type rhamnan di- and trisaccharide in moderate yields. Once these targets were achieved, a process to use SO3 center dot pyridine complex in DMF for sulfation compatible with an automated solution-phase liquid handling system was developed and successfully applied to carbohydrate sulfation to create two rhamnan sulfate fragments with differing monosulfation patterns.
Reference of 24057-28-1, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 24057-28-1.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem