Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 3731-52-0, Name is Pyridin-3-ylmethanamine, SMILES is NCC1=CC=CN=C1, in an article , author is Shi, Qiangqiang, once mentioned of 3731-52-0, Quality Control of Pyridin-3-ylmethanamine.
C-28 steroids from the fruiting bodies of Ganoderma resinaceum with potential anti-inflammatory activity
Eight undescribed ergostane-type steroids, (22E,24R)-ergosta-7,22-dien-3 beta,5 alpha-diol- 6,5-olide, (22E,24R)-er-gosta-7,9(11),22-trien-3 beta,5 beta,6 beta-triol, (22E,24R)-6 beta-methoxy ergosta-7,9(11),22-trien-3 beta,5 alpha,14 beta-triol, (22E,24R)-9 alpha,15 alpha-dihydroxyergosta-4,6,8 (14),22-tetraen-3-one, (22E,24R)-ergosta-5,8,22-trien-3 beta,11 alpha-dihydroxyl-7-one, (22E,24R)-ergosta-4,7,22-trien-3 beta,9 alpha,14 beta-trihydroxy1-6-one, (22E,24R)-ergosta-7,22- dien-3 beta,9 alpha,14 beta-trihydroxy1-6-one, and (22E,24R)-6 beta-methoxyergosta-7,22-dien-3 beta, 5 alpha,9 alpha,14 beta-tetraol, and twentyone known analogues were isolated from the fruiting bodies of Ganoderma resinaceum Boud. Their chemical structures were determined on the basis of comprehensive spectroscopic analysis and X-ray crystal diffraction, as well as empirical pyridine-induced deshielding effects. Furthermore, selected compounds were evaluated for their inhibitory effects on macrophage activation using an inhibition of nitric oxide production assay. Finally, (22E,24R)-ergosta-5,8,22- trien-3/3,11 alpha-dihydroxy1-7-one, (22E,24R)-ergosta-4,7,22-trien-3 beta,9 alpha,14 beta-tri hydroxyl-6-one, (22E,24R)-6 beta-methoxyergosta-7,22-dien-3 beta,5 alpha,9 alpha,14 beta-tetrao1, (22E,24R)-ergosta-6,9,22-trien-3 beta,5 alpha,8 alpha-triol,ergost-6,22-dien-3 beta,5 alpha,8 alpha-triol, 5 alpha,6 alpha-epoxy-(22E,24R)-ergosta-8,22-diene-3 beta,7 alpha-diol, 5 alpha,6 alpha-epoxy-(22E,24R)- ergosta-8(14),22-diene-3 beta,7 alpha-diol, 5 alpha,6 alpha-epoxy-(22E,24R)-ergosta-8(14),22-diene-3 beta, 7 beta-diol, and 22E-7 alpha-methoxy-5 alpha,6 alpha-epoxyergosta-8(14),22-dien-3 beta-ol showed inhibitory effects on NO production with IC50 values ranging from 3.24 +/- 0.02 to 35.19 0.41 mu M compared with L-NMMA (IC50 49.86 +/- 2.13 mu M), indicating that they have potential anti-inflammatory activity.
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem