Related Products of 62936-56-5, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 62936-56-5, Name is Sodium 4-(nicotinamido)butanoate, SMILES is O=C([O-])CCCNC(C1=CC=CN=C1)=O.[Na+], belongs to pyridine-derivatives compound. In a article, author is Veerakanellore, Giri Babu, introduce new discover of the category.
Synthesis of 1H-Pyrazol-5-yl-pyridin-2-yl-[1,2,4]triazinyl Soft-Lewis Basic Complexants via Metal and Oxidant Free [3+2] Dipolar Cycloaddition of Terminal Ethynyl Pyridines with Tosylhydrazides
Soft-Lewis basic complexants that facilitate chemoselective separation of the minor actinides from the lanthanides are critical to the closure of the nuclear fuel cycle. Complexants that modulate covalent orbital interactions with relevant metals of interest can facilitate desired outcomes in liquid-liquid separation, allowing for further transmutative processes that decrease issues related with storage of spent nuclear fuel from energy and weapons production. Synthesis of previously unexplored scaffolds seeks to improve performance over benchmark complexants. In the current work, an intermolecular, thermally initiated, and DBU-assisted [3 + 2] cycloaddition of 3-(6-ethynyl-pyridin-2-yl)-5,6-diphenyl-[1,2,4]triazine dipolarophiles with structurally diverse 4-methylbenzenesulfono-hydrazides afforded 21 yet-to-be reported examples in 42-68% yield and modest regioselectivity for the desired regioisomer. Preparation of requisite starting materials, method definition, dipole and dipolarophile scope, ten-fold scale-up reaction, and downstream functional group interconversion are reported herein.
Related Products of 62936-56-5, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 62936-56-5 is helpful to your research.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem