Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 19798-80-2, Name is 4-Chloropyridin-2-amine, SMILES is ClC1=CC(N)=NC=C1, belongs to pyridine-derivatives compound. In a document, author is Ye, Pengqing, introduce the new discover, Category: pyridine-derivatives.
Rare-Earth-Metal-Catalyzed Synthesis of Azaindolines and Naphthyridines via C-H Cyclization of Functionalized Pyridines
We report herein a rare-earth-metal-catalyzed insertion of a 2-pyridine C(sp(2))-H bond into an intramolecular unactivated vinyl bond. This reaction provides streamlined access to a range of azaindolines in moderate to excellent yields. The salient features of this reaction include simple and mild reaction conditions, 100% atom efficiency, and wide substrate scope. This methodology is also used to construct other nitrogen-containing compounds such as naphthyridine derivatives. A plausible mechanism for the formation of azaindolines involving initial C-H bond activation by the lanthanide complex followed by C=C insertion into a Ln-C bond to form an alkyl lanthanide species that subsequently undergoes cyclization is proposed.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 19798-80-2 is helpful to your research. Category: pyridine-derivatives.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem