Chemistry, like all the natural sciences, begins with the direct observation of nature— in this case, of matter.120202-71-3, Name is (R)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate, SMILES is O=C(OC)[C@@H](C1=CC=CC=C1Cl)N2CCC3=C(C=CS3)C2.O=S(O)(O)=O, belongs to pyridine-derivatives compound. In a document, author is Guo, Yang, introduce the new discover, Application In Synthesis of (R)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate.
Catalytic Hydrodenitrogenation of Pyridine under Hydrothermal Conditions: A Comprehensive Study
This article focuses on the kinetic modeling and catalytic performance of hydrodenitrogenation of pyridine under hydrothermal conditions. Piperidine derivatives are the major nitrogen-containing intermediates, including 1-piperidinecarboxaldehyde, 1-piperidineethanol, and alkyl piperidines. Catalysts overall improved the formation of N-free products including 1-pentanol and 2-methyl-1-pentanol. Commercial Pd/C provided the highest pyridine conversion rate at 350 degrees C, while the homemade Ni-Ru bimetallic catalyst provided a prominent denitrogenation activity at 400 degrees C, leading to the highest 1-pentanol yield as a major denitrogenated product. Conversion of pyridine over the Ni50Ru50/C catalyst led to formation of three major alkyl piperidines (1-ethyl piperidine, 1-methyl piperidine, and 1-pentyl piperidine). These alkyl piperidine intermediates could further be converted into amino and N-free compounds. A kinetic model was developed to mathematically describe the hydrothermal HDN reaction of pyridine over the Ni50Ru50/C catalyst, which clearly captured all data trends and fitted the temporal variation of all major products. Sensitivity analysis suggested that dehydrogenation from piperidine to pyridine has a strong impact on the whole reaction pathways.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 120202-71-3 is helpful to your research. Application In Synthesis of (R)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem