Synthetic Route of 127978-70-5 ,Some common heterocyclic compound, 127978-70-5, molecular formula is C7H9NO2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
3-(2-fluoroethoxy)-2-[[4-[1-(3-fluoropropyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]pyridine.succinate (B-13) Following the procedure for the preparation of compound B-5, but substituting (5-methoxypyridin-2-yl)methanol for [3-(2-fluoroethoxy)-pyridin-2-yl]-methanol and 1-10 for intermediate compound 1-8, provided final compound B-13 that was converted into the corresponding succinic acid salt, in a similar way as it is described above for final compound B-3, which was crystallized from diethyl ether/diiisopropyl ether yielding the succinic acid salt of final compound B-13 (39.2%) as a white solid.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 127978-70-5, (5-Methoxypyridine-2-yl)methanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Andres-Gil, Jose Ignacio; De Angelis, Meri; Bormans, Guy Maurits R.; Celen, Sofie Jeanne Leopoldine; US2012/213703; (2012); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem