Simple exploration of N-Hydroxynicotinimidamide

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1594-58-7, N-Hydroxynicotinimidamide, and friends who are interested can also refer to it.

Synthetic Route of 1594-58-7, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 1594-58-7, name is N-Hydroxynicotinimidamide. A new synthetic method of this compound is introduced below.

General procedure: 0.002 mol amidoximes and 0.008 mol triethylamine dissolved in 10 ml dichloromethane. The solution was then instilled to 10 ml dichloromethane containing 0.004 mol Vilsmeier salt and stirred for 4 h . The whole progress was monitored by TLC and evaporated the solvent then followed by column chromatography column chromatography to get terminated material.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1594-58-7, N-Hydroxynicotinimidamide, and friends who are interested can also refer to it.

Reference:
Article; Su, Dongshan; Duan, Haifeng; Wei, Zhonglin; Cao, Jungang; Liang, Dapeng; Lin, Yingjie; Tetrahedron Letters; vol. 54; 50; (2013); p. 6959 – 6963;,
Pyridine – Wikipedia,
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