Application of 6332-56-5, Adding some certain compound to certain chemical reactions, such as: 6332-56-5, name is 3-Nitropyridin-2(1H)-one,molecular formula is C5H4N2O3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6332-56-5.
2-Oxo-3-nitro-N-(carbomethoxymethyl)-pyridinone (109). 2-Hydroxy-3-nitropyridine 108 (10 g, 71.38 mmole) is mixed with pulverized potassium carbonate (10.9 g, 78.5 mmole) and 30 mL of DMF. After 10 min, methyl bromoacetate (10.4 mL, 107 mmole) is added. The resulting mixture is stirred at room temperature for 4.5 hr. The reaction is quenched by water and extracted by ethyl acetate. The organic layer is then washed with brine, dried over MgSO4, filtered and evaporated to give an oil which is chromatographed over flash silica with EtOAc to give 109.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 6332-56-5, 3-Nitropyridin-2(1H)-one, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; The Procter & Gamble Company; US5672598; (1997); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem