Adding a certain compound to certain chemical reactions, such as: 5969-83-5, 2-(4-Chlorophenyl)pyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: 2-(4-Chlorophenyl)pyridine, blongs to pyridine-derivatives compound. name: 2-(4-Chlorophenyl)pyridine
General procedure: A mixture of aryl halide (0.5 mmol), phenylboronic acid(0.5 mmol), K2CO3 (0.5 mmol), and nano-Pd/Fe3O4/ZnO(0.003 g, contain 9.7 × 10-5 mol% Pd), and H2O (1 mL) was stirred at 100 C in an oil bath under air atmosphere. After completion of the reaction, the catalyst was removed by a magnet and the resulting mixture was quenched with water and extracted with EtOAc (2 × 10 mL). The combined organic layer was dried over anhydrous sodium sulfate(Na2SO4) and evaporated in a rotary evaporator under reduced pressure. Resulting product was purified by column chromatography on silica gel using n-hexane/ethylacetate (5:1) as eluent to afford the pure product.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,5969-83-5, 2-(4-Chlorophenyl)pyridine, and friends who are interested can also refer to it.
Reference:
Article; Hosseini-Sarvari, Mona; Khanivar, Ameneh; Moeini, Fatemeh; Journal of the Iranian Chemical Society; vol. 13; 1; (2016); p. 45 – 53;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem