With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.13362-78-2, name is (E)-1,2-Di(pyridin-4-yl)ethene, molecular formula is C12H10N2, molecular weight is 182.22, as common compound, the synthetic route is as follows.HPLC of Formula: C12H10N2
A mixture of ZnCl2(20 mg, 0.147 mmol), H4L(12 mg,0.02 mmol), dpe (9 mg, 0.05 mmol), CH3CN(2 mL),water (1 mL) and HCl (150muL of 6 mol/L) was sealed in an autoclave equipped with a Teflon liner (25 mL). The mixture was heated at 120 °C for 3 days, then cooled to roomtemperature. Colorless rod-shaped crystals of 2 were collected in ca. 32percent yield based on H4L. Elemental analysis for C114H92N8O28Zn4,calcd (percent): C, 59.96; H, 4.06; N, 4.91.Found (percent): C, 59.02; H, 4.17; N, 4.83. IR data (KBr, cm?1):3417 (s), 2360 (w), 2068 (w), 1672 (s), 1613 (s), 1560 (m), 1504 (m), 1430 (s), 1303 (m), 1228 (m), 1127 (s), 1072 (s),1026 (s), 976 (s), 844 (s), 616 (m), 569 (s), 548 (s), 511 (w).
At the same time, in my other blogs, there are other synthetic methods of this type of compound,13362-78-2, (E)-1,2-Di(pyridin-4-yl)ethene, and friends who are interested can also refer to it.
Reference:
Article; Wei, Jia; Zhou, Ting; Zuo, Yuxiang; Cheng, Wei-Wei; Liu, Mei-Pin; Bian, Rong-Rong; Chen, Ning-Ning; Xue, Yun-Shan; Tao, Jian-Qing; Transition Metal Chemistry; vol. 43; 6; (2018); p. 529 – 537;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem