Reference of 633328-33-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 633328-33-3, name is 3-Bromo-1H-pyrazolo[4,3-b]pyridine. This compound has unique chemical properties. The synthetic route is as follows.
Step 2: Preparation of 3-Bromo-l-(4-methoxybenzyl)-lH-pyrazolo[4,3-b]pyridine(Exp-l-g3)[0087] Into 8 mL of DMF was placed 1.0 g of Exp-l-g2 (5 mmol) prepared in Step 1 , 0.94 g p-methoxybenzylchloride (PMBC1, 6 mmol) and 1.38g K2C03 (10 mmol). The reaction mixture thus provided was stirred for 3 hours while maintaining it at 100 C. At the end of this time the reaction mixture was diluted with 150 mL ethylacetate (EtOAc). The diluted mixture was washed sequentially with ali quotes of brine then water, dried over MgSC>4, filtered, and concentrated. The concentrate solution thus provided was purified via silica column chromatogram (PE:EtOAc = 8: 1) and after the eluting solvent was evaporated gave Exp-l-g3 as a yellow solid (1.2 g, 75 %).
According to the analysis of related databases, 633328-33-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MERCK SHARP & DOHME CORP; ADDEX PHARMA S.A.; LIVERTON, Nigel; JONES, Philip; BOLEA, Christelle; CELANIRE, Sylvain; TANG, Lam; BOUDOU, Cedric; LEI, Zhiyu; LIU, Fuqing; LUO, Yunfu; DONG, Jingchao; SOLL, Richard; WO2013/60029; (2013); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem