Electric Literature of 101083-92-5, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 101083-92-5, name is 5-Nitro-1H-pyrrolo[2,3-b]pyridine. A new synthetic method of this compound is introduced below.
2.675 g 5-Nitro-lH-pyrrolo[2,3-b]pyridine in 200 ml THF were hydrogenated over 1.0 g Platinum on carbon at atmospheric pressure for 3 hrs at RT (with thin layer chromatography (TLC) control). The catalyst was removed by filtration, the filtrate was evaporated and the residue purified by chromatography on silica in ethyl acetate /heptane mixtures. Yield 1.84 g
At the same time, in my other blogs, there are other synthetic methods of this type of compound,101083-92-5, 5-Nitro-1H-pyrrolo[2,3-b]pyridine, and friends who are interested can also refer to it.
Reference:
Patent; F. HOFFMANN-LA ROCHE AG; WO2008/28617; (2008); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem