Application of 91872-10-5 , The common heterocyclic compound, 91872-10-5, name is 3,5-Dibromo-6-methyl-2-pyridinamine, molecular formula is C6H6Br2N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Reference Example 245 N-[(3,5-dibromo-6-methylpyridin-2-yl)carbamothioyl]benzamide An acetone solution (14.0 mL) of 2-amino-3,5-dibromo-6-methylpyridine (5.05 g) and benzoyl isothiocyanate (3.25 g) was heated under reflux for 8 h After cooling to room temperature, diisopropy ether was added, and the resulting solid was collected by filtration and dried to give the title compound (6.67 g). MS(ESI)m/z; 428,430,432[M+H]+
The synthetic route of 91872-10-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Mitsubishi Tanabe Pharma Corporation; OKUYAMA, Masahiro; FUKUNAGA, Kenji; USUI, Kenji; HAYASHI, Norimitsu; IIJIMA, Daisuke; HORIUCHI, Hideki; FUJIMOTO, Nobuaki; (218 pag.)EP3372601; (2018); A1;,
Pyridine – Wikipedia,
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