Reference of 6959-47-3, Adding some certain compound to certain chemical reactions, such as: 6959-47-3, name is 2-(Chloromethyl)pyridine hydrochloride,molecular formula is C6H7Cl2N, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6959-47-3.
General procedure: N-ethyl diamine (550 mg, 6.24 mmol) was dissolved inCH2Cl2 (10 mL). Chloromethyl pyryidine HCl salt (3.07 g, 18.71 mmol)was added followed by water (10 mL). Solution of NaOH in water (1.8 gin 6 mL) was added drop wise and the reaction mixture was stirred atRT for 3 days. Water (50 mL) was added and product was extracted withCH2Cl2 (3×20 mL), dried over MgSO4, solvent volume reduced to ca.10 mL under vacuum and transferred to short chromatographic columnand purified with EtOAc/MeOH gradient (0-30% MeOH). All productswere isolated as viscous orange oils
According to the analysis of related databases, 6959-47-3, the application of this compound in the production field has become more and more popular.
Reference:
Article; Schaefer-Ramadan, Stephanie; Barlog, Maciej; Roach, Jim; Al-Hashimi, Mohammed; Bazzi, Hassan S.; Machaca, Khaled; Bioorganic Chemistry; vol. 87; (2019); p. 366 – 372;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem