Related Products of 70298-89-4, Adding some certain compound to certain chemical reactions, such as: 70298-89-4, name is 2,2-Dimethyl-N-pyridin-4-yl-propionamide,molecular formula is C10H14N2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 70298-89-4.
General procedure: To a stirred solution of 1a (0.36 g, 2.0mmol) in THF (5 mL) at ?78 C was added n-BuLi (1.6 M in hexane; 4.0 mmol) dropwise. After 15 min,temperature was raised to 0 C and stirring was continued for 2.5 h. Then, the mixture was cooled to ?78C and MeCOCO2Me (0.20 g, 2.0 mmol) was added dropwise. The resulting mixture was graduallywarmed to 0 C, treated with saturated aqueous NH4Cl (20 mL), and extracted with AcOEt (3 × 15 mL).The combined extracts were washed with brine (15 mL), dried (Na2SO4), and concentrated by evaporation.The residue was purified by column chromatography on SiO2 (AcOEt/hexane 1:3) to afford 2a (0.28 g,50percent);
According to the analysis of related databases, 70298-89-4, the application of this compound in the production field has become more and more popular.
Reference:
Article; Kobayashi, Kazuhiro; Kosuna, Risa; Chikazawa, Yuuki; Heterocycles; vol. 92; 9; (2016); p. 1643 – 1653;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem