Simple exploration of Methyl 4-chloropicolinate

According to the analysis of related databases, 24484-93-3, the application of this compound in the production field has become more and more popular.

Related Products of 24484-93-3, Adding some certain compound to certain chemical reactions, such as: 24484-93-3, name is Methyl 4-chloropicolinate,molecular formula is C7H6ClNO2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 24484-93-3.

13 g (62.5 MMOL) 1 are dissolved together with 2.98 g (31.24 MMOL) dry magnesiumchloride in THF. After 5 min 110 ML METHYLAMIN-SOLUTION (2M in THF) are added dropwise within 10 min and the suspension stirred for 2 h at room temperature. 120 ml water und 63 mL 1 M HCI-SOLUTION are added and the mixture is extracted three times with ethyl acetate. The combined organic phases are washed with brine, dried with NA2SO4, filtered and evaporated. Yield : 10.5 g (98. 5 %) 2, colourless oil.

According to the analysis of related databases, 24484-93-3, the application of this compound in the production field has become more and more popular.

Reference:
Patent; MERCK PATENT GMBH; WO2005/4864; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem