Electric Literature of 73257-49-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 73257-49-5, name is Dimethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate. This compound has unique chemical properties. The synthetic route is as follows.
General procedure: 1,4-DHPs (1 mmol, dissolved in 10 mL acetonitrile), TEMPO(0.05 mmol), FeCl3·6H2O (0.05 mmol), NaNO2 (0.05 mmol) and CH3COOH (1 mL) were added successively to a 25 mL three-neckedround-bottom flask equipped with a magnetic stirrer and a thermometer. The resulting mixture was stirred at room temperature and ambient pressure with an oxygen balloon until the reaction was completed as monitored by TLC (5:1 ethyl acetate/petroleum ether as eluent). Saturated aqueous NaHCO3 solution was added to make it neutral. The mixture was extracted with ethyl acetate three times. The combined organic extracts were washed with saturated aqueous NaCl solution, dried over MgSO4 and filtered. After removal of the solvent under reduced pressure, the residue was purified by columnchromatography (10:1 ethyl acetate/petroleum ether as eluent). Dimethyl 4-(4-chlorophenyl)-2,6-dimethyl-3,5-pyridinedicarboxylate(2l): Pale yellow solid, m.p. 138-140 C (lit.[24] 137-139 C). 1H NMR (500 MHz, CDCl3): delta 7.37 (d, J = 8 Hz, 2H), 7.19 (d, J = 8 Hz, 2H), 3.58 (s, 3H), 2.60 (s, 3H).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 73257-49-5, Dimethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate.
Reference:
Article; Lou, Bin-Hui; Chen, Shu-Bin; Wang, Jian; Chen, Ying; Li, Jing-Hua; Journal of Chemical Research; vol. 37; 7; (2013); p. 409 – 412;,
Pyridine – Wikipedia,
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