Adding a certain compound to certain chemical reactions, such as: 717106-69-9, Methyl 2-(6-chloropyridin-3-yl)acetate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 717106-69-9, blongs to pyridine-derivatives compound. COA of Formula: C8H8ClNO2
A solution of 1.45 g (7.84 MMOL) of Preparatory Compound A in 10 mL of 40% aqueous METHYLAMINE in acetonitrile was stirred vigorously at room temperature (about 22 C) and monitored by reverse-phase chromatography until the reaction was complete. The solvents were removed under reduced pressure and the solid residue dried in a vacuum oven at 50 C overnight to give 1.39 g (96%) of Preparatory Compound B, 2- (6-CHLORO-3-PYRIDINYL)-N-METHYLACETAMIDE, as a light brown solid : H NMR (CDC . S) 8 8.30 (d, J = 3.0 Hz, i H), 7.68 (dd, J = 3.0 and 8.0 Hz, 1 H), 7.34 (d, J = 8.0 Hz, 1 H), 5.50 (bs, 1 H), 3.54 (s, 2H), 2.83 (d, J = 4.8 Hz, 3H) ppm. GCMS: (EI) m/z 184 (M+).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,717106-69-9, its application will become more common.
Reference:
Patent; DOW AGROSCIENCES LLC; WO2004/57960; (2004); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem