A new synthetic route of 77992-44-0

According to the analysis of related databases, 77992-44-0, the application of this compound in the production field has become more and more popular.

Electric Literature of 77992-44-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 77992-44-0, name is (5-Bromopyridin-2-yl)hydrazine. This compound has unique chemical properties. The synthetic route is as follows.

5-Bromo-2-hydrazinylpyridine (2.00 g, 10.6 mmol) in THF (20 mL) was treated with CDI (2.59 g, 15.9 mmol) at rt and then stirred at reflux overnight. The reaction was diluted with water (50 mL) and extracted in EtOAc (2*50 mL). The combined organic layers were washed with brine (50 mL), dried with Na2SO4, and concentrated to give 6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (1.50 g, 67%); ESI+ve 213.85 [M+1].

According to the analysis of related databases, 77992-44-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; FLATLEY DISCOVERY LAB; Cole, Bridget M.; Nugent, Richard A.; Smith, JR., Paul T.; (82 pag.)US2016/96835; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem