The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 58584-94-4, name is 2,6-Dichloro-3-methylpyridine. This compound has unique chemical properties. The synthetic route is as follows. category: pyridine-derivatives
Step 2. To 3-(tributylstannyl)-2-(trifluoromethyl)imidazo[l,2-a]pyridine (1.1 g, 2.31 mmol) was added the obtained product, dioxane (6 mL), QPhos (49 mg, 0.07 mmol) and Pd2dba3 (21 mg, 0.023 mmol). The mixture was heated at 110 C for one hour, then at 90 C for 15 hours. The product was concentrated and purified by chromatography on silica gel (gradient ethyl acetate :hexane 1:10 to 1:1) to provide a mixture of crude isomers: 3-(6- chloro-5-methylpyridin-2-yl)-2-(trifluoromethyl)imidazo[l,2-a]pyridine as a pink solid (58 mg, 8 ) and 3-(6-chloro-3-methylpyridin-2-yl)-2-(trifluoromethyl)imidazo[l,2-a]pyridine (more polar) (130 mg).
With the rapid development of chemical substances, we look forward to future research findings about 58584-94-4.
Reference:
Patent; PTC THERAPEUTICS, INC.; BAIAZITOV, Ramil; CHOI, Soongyu; DU, Wu; HWANG, Seongwoo; LEE, Chang-Sun; LIU, Ronggang; MOON, Young-Choon; PAGET, Steven, D.; REN, Hongyu; SYDORENKO, Nadiya; WILDE, Richard, Gerald; WO2015/76800; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem