Reference of 884495-36-7, Adding some certain compound to certain chemical reactions, such as: 884495-36-7, name is 6-Chloro-2-methylnicotinaldehyde,molecular formula is C7H6ClNO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 884495-36-7.
A mixture of 6-chloro-2-methylpyridine-3-carboxaldehyde (3.00 g, 19.3 mmol), A- mercaptophenol (90% pure, 2.7Og, 19.3 mmol) and K2CO3 (1.66 g, 12.0 mmol) in DMF (20 mL) was stirred at room temperature for 16 h. Bromoacetic acid tert-butyl ester (6.00 g, 30.8 mmol) and K2CO3 (3.40 g, 24.6 mmol) were added, and the mixture was stirred for another 4 h. Aqueous work-up and purification by flash chromatography on silica gel (EtOAc/hexanes, 1 :4 in v/v) afforded 4-(5-fo?nyl~6-methyl-rhoyridin-2-ylsulfanyl)-benzoic acid tert-butyl ester as EPO
According to the analysis of related databases, 884495-36-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ANORMED INC.; WO2007/22371; (2007); A2;,
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