Extracurricular laboratory: Synthetic route of (6-Methoxypyridin-3-yl)methanol

Statistics shows that 58584-63-7 is playing an increasingly important role. we look forward to future research findings about (6-Methoxypyridin-3-yl)methanol.

Synthetic Route of 58584-63-7, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.58584-63-7, name is (6-Methoxypyridin-3-yl)methanol, molecular formula is C7H9NO2, molecular weight is 139.15, as common compound, the synthetic route is as follows.

To a solution of the above compound (1.00 g, 7,19 mmoi) in 25 mL of dichloromethane at 0 C was added thionyl chloride (1.57 mL, 21.6 mmoi). After 15 h, the mixture was concentrated in vacuo to provide 5-(chloromethyl)-2-methoxypyridine.

Statistics shows that 58584-63-7 is playing an increasingly important role. we look forward to future research findings about (6-Methoxypyridin-3-yl)methanol.

Reference:
Patent; MERCK SHARP & DOHME CORP.; KUDUK, Scott, D.; SKUDLAREK, Jason, W.; WO2011/159553; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem