Related Products of 13534-97-9 ,Some common heterocyclic compound, 13534-97-9, molecular formula is C5H5BrN2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Step 1; To a solution of 2-bromo-5-aminopyridine (3 g, 17.3 mmol) and potassium thiocyanate (4.2 g) in acetic acid (20 mL), bromine (3.3 g) was added dropwise under icebath-cooling. The solution was then stirred for 1 hour and subsequently at 100°C overnight. After the reaction mixture was cooled, water was added thereto. The precipitate was collected by filtration, then subjected to a next reaction without further purification.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,13534-97-9, its application will become more common.
Reference:
Patent; Shionogi & Co., Ltd.; EP2426135; (2012); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem