Reference of 588729-99-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 588729-99-1, name is 3-Amino-5-bromo-2-chloropyridine. This compound has unique chemical properties. The synthetic route is as follows.
Step 1: The 2-chloro-3-amino-5-bromo pyridine (500 mg, 2 . 46mmol) was dissolved in THF (10 ml), added LiHMDS (7.4 ml, 7 . 4mmol), stirring for ten minutes, then adding 4-fluorobenzenesulfonyl chloride (1.44g, 7 . 4mmol), stir at room temperature overnight. By adding dichloromethane (20 ml) dilution, washed with saturated sodium bicarbonate, with dichloromethane (4×30 ml) extraction, combined organic phase, dried, concentrated, the residue column chromatography (petroleum ether: ethyl acetate = 20:1) shall be N-(5-bromo-2-chloro-pyridine-3-yl) – 4-fluorobenzene sulfonaide (770 mg, 87%).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 588729-99-1, 3-Amino-5-bromo-2-chloropyridine.
Reference:
Patent; Shanghai Huilun Life Sciences & Technology Co., Ltd.; Cheng, Jianjun; Qin, Jihong; (61 pag.)CN103936762; (2016); B;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem