Adding a certain compound to certain chemical reactions, such as: 54221-96-4, 6-Methoxypicolinaldehyde, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 54221-96-4, blongs to pyridine-derivatives compound. Recommanded Product: 6-Methoxypicolinaldehyde
6-Methoxy-2-pyridinecarboxaldehyde (2.0 mL, 16.63 mmol) and 2,6-dimethylaniline(2.07 mL, 16.74 mmol) were dissolved in 30 mL of anhydrous methanol and the resultingmixture was allowed to stir magnetically for 5 h at room temperature. The solvent wasremoved under reduced pressure to give yellow powders. Yield: 2.53 g (63percent). Anal. Calcd(percent) for C15H16N2O (M = 240.31 g mol?1): C, 74.97; H, 6.71; N, 11.66. Found: C, 74.85; H, 6.72; N,11.62. FT-IR (KBr, cm-1): 3426(w), 3073(w), 2942(w), 2852(w), 1652(s), 1589(s), 1572(m),1539(w), 1466(s), 1443(m), 1412(w), 1378(w), 1334(m), 1324(m), 1267(s), 1232(w), 1195(m),1148(m), 1087(w), 1039(m), 985(w), 958(w), 915(w), 856(m), 805(m), 788(w), 768(s), 739(w),730(w), 690(w), 617(w), 562(w), 511(w), 487(w), 464(w). 1H NMR (400 MHz, CDCl3): delta 8.21 (s,1H, CH = N), 7.85 (d, 1H, Py-H5), 7.71 (t, 1H, Py-H4), 7.58 (d, 1H, Py-H3), 6.85?7.08 (m, 3H,Ph-H3,4,5), 3.99 (s, 3H, ?OCH3), 2.16 (s, 6H, ?CH3) ppm.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,54221-96-4, its application will become more common.
Reference:
Article; Dong, Yu-Wei; Wang, Ping; Fan, Rui-Qing; Chen, Wei; Wang, A-Ni; Yang, Yu-Lin; Journal of Coordination Chemistry; vol. 70; 11; (2017); p. 1953 – 1972;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem