Introduction of a new synthetic route about 136818-50-3

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 136818-50-3, 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid.

Electric Literature of 136818-50-3, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 136818-50-3, name is 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, molecular formula is C8H6N2O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

Example 13Synthesis of3- ( (dimethylamino) methyl) -lH-pyrrolo [2, 3-£>]pyridine-2- carboxylic acid19Treatment of 2 with a mixture of dimethylamine and aqueous formaldehyde gives3- ( (dimethylamino) methyl) -lH-pyrrolo [2 , 3-£>]pyridine-2-carboxyl ic acid (19) by Mannich reaction.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 136818-50-3, 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid.

Reference:
Patent; IRONWOOD PHARMACEUTICALS INCORPORATED; LUDRIGAN, Regina; JEFFREY, John; MERMERIAN, Ara; WO2010/5528; (2010); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem