Adding a certain compound to certain chemical reactions, such as: 2176-62-7, Perchloropyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: Perchloropyridine, blongs to pyridine-derivatives compound. name: Perchloropyridine
In a 1000 mL three-necked flask, add 600 mL of DMI and anhydrous KF146.72 g with a purity of 99% and a particle size of 20-50 um. Stirring and distilling under reduced pressure (130-135 C / 60 mmHg)60 g solvent with water evaporation, the measured water content of less than 1000 ppm, heated to 90 C, adding purity of 97% of the five chloropyridine 129.40 g, After 1.5 h of incubation, heating was stopped, the reaction mixture was cooled and the reaction mixture was filtered to obtain filtrate and residue. The residue was washed with 100 mL of DMI and suction filtered to obtain a washing solution. Combined washing liquid and filtrate, distillation, collecting 65 ~ 70 , 5 KPa fractions, namely 3,5-dichloro-2,4,6-trifluoropyridine
At the same time, in my other blogs, there are other synthetic methods of this type of compound,2176-62-7, Perchloropyridine, and friends who are interested can also refer to it.
Reference:
Patent; Sichuan Fusida Biotechnology Development Co., Ltd; Luo, Qian; Peng, Zhou; Li, Zhou; Wang, Lei; Zhang, Hua; Pi, Yawei; (8 pag.)CN106008331; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem