Electric Literature of 7169-97-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 7169-97-3, name is N-(5-Bromopyridin-2-yl)acetamide. This compound has unique chemical properties. The synthetic route is as follows.
N-(5-bromopyridin-2-yl)acetamide (4.30 g, 20 mmol),P-carboxyphenylboronic acid(3.66 g, 22 mmol) was added to a 250 ml pear-shaped bottle.Further, cesium carbonate (13.0 g, 40 mmol) and tetrakistriphenylphosphine palladium (1.2 g, 1 mmol) were successively added.Add acetonitrile/water to the above mixture (V:V=3:2)200ml. N2 protection, the oil bath was heated to 90 C for 48 h. After the reaction,The reaction solution was cooled to room temperature and suction filtered.The filtrate was adjusted to pH 4 with 6 mol/L hydrochloric acid, and a white solid was precipitated.The filter cake was vacuum dried to give the product 3.89 g, yield 76%.
According to the analysis of related databases, 7169-97-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Xi’an Jiaotong University; Zhang Jie; Pan Xiaoyan; Liang Liyuan; Lu Wen; Wang Sicen; He Langchong; Si Ru; Wang Jin; (14 pag.)CN109651243; (2019); A;,
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