Electric Literature of 98-98-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 98-98-6, name is Picolinic acid. This compound has unique chemical properties. The synthetic route is as follows.
1) Synthesis of (4-Chloropvridine-2-carboxylic acid)-methvlamide (2) ci I 1. SOC12 CH NH DMF MgClz _ O THF O 2. MeOH N N Toluene 1 60 ml of thionylchloride are heated to 45 C under a N2 atmosphere, and slowly mixed with 1.83 ml dimethyl formamide. To this solution, 20 g of pyridine-2-carboxylic acid are added portion wise. The reaction mixture is stirred for another 15 min at 45 C and subsequently kept at 80 C for 24 hours. The reaction mixture is evaporated to dryness, the residue is stripped several times with water free toluene. The oil obtained by this procedure is dissolved in toluene, chilled to 0 C, slowly mixed with methanol and stirred for 1 hour. The precipitated solid is separated by suction filtration, washed with toluene and recrystallized from acetone. Yield : 15 g (44 %) of 1, colorless crystals
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 98-98-6, Picolinic acid.
Reference:
Patent; MERCK PATENT GMBH; WO2005/58832; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem