Related Products of 155377-05-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 155377-05-2, name is Methyl 6-(trifluoromethyl)picolinate. This compound has unique chemical properties. The synthetic route is as follows.
The biuret (13 g, 126.3 mmol) was dissolved in 300 mL of ethylene glycol dimethyl ether.Sodium hydride (42 g, 1053 mmol) was added portionwise and stirred at 50 C for 1 h.Add 6-(trifluoromethyl)-picolinic acid methyl ester (21.6 g, 105.3 mmol),heatingThe reaction was carried out at 85 C for 16 h.The reaction solution was poured into water, the pH was adjusted with concentrated hydrochloric acid, filtered, and the filter cake was dried.The title compound was obtained.
According to the analysis of related databases, 155377-05-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Nanjing Shenghe Pharmaceutical Co., Ltd.; Zhao Liwen; Zhang Jin; Chen Cheng; Xu Chenglong; Wang Cheng; (19 pag.)CN110054616; (2019); A;,
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