Adding a certain compound to certain chemical reactions, such as: 18364-47-1, N-Methylpyridin-3-amine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 18364-47-1, blongs to pyridine-derivatives compound. category: pyridine-derivatives
A mixture of 5.65 g (35.1 mmol) (IV-1), 75 mol of anhydrous pyridine and 4.19 g (38.7 mmol) of 3-methylaminopyridine was heated to reflux under argon for 8 hours, freed of the solvent under reduced pressure and the residue was stirred with 100 ml of ethanol and 0.1 mol of potassium carbonate at room temperature for one hour, the solid filtered off and the filtrate evaporated to dryness. The product was obtained from the residue by chromatography on silica gel using a mixture of dichloromethane and methanol. 1H-NMR (DMSO-d6, 600 MHz); delta=3.24 (s, 3H), 3.31 (s, 3H), 5.83 (s, 1H), 7.43-7-45 (m, 1H), 7.80-7.82 (m, 1H), 8.47-8.48 (m, 1H), 8.52 (m, 1H), 10.38 (s, 1H) ppm.1H-NMR (CD3CN, 400 MHz); delta=3.30 (s, 3H), 3.35 (s, 3H), 5.69 (s, 1H), 7.35-7-39 (m, 1H), 7.65-7.68 (m, 1H), 8.45-8.48 (m, 2H), 8.73 (br. s, 1H) ppm.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,18364-47-1, its application will become more common.
Reference:
Patent; Bayer CropScience Aktiengesellschaft; JANSEN, Johannes-Rudolf; HEIL, Markus; FISCHER, Reiner; WILCKE, David; WILLOT, Matthieu; ILG, Kerstin; EILMUS, Sascha; LOeSEL, Peter; ANDERSCH, Wolfram; (67 pag.)US2019/40042; (2019); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem