Analyzing the synthesis route of 2-(Chloromethyl)pyridine hydrochloride

According to the analysis of related databases, 6959-47-3, the application of this compound in the production field has become more and more popular.

Electric Literature of 6959-47-3, Adding some certain compound to certain chemical reactions, such as: 6959-47-3, name is 2-(Chloromethyl)pyridine hydrochloride,molecular formula is C6H7Cl2N, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6959-47-3.

General procedure: L1 was prepared by a similar procedure as described in the literature [24,39-41]. A water solution (15.0mL) of cyclopentylamine (1.70g, 0.020mol) was added to a water solution (15.0mL) of 2-picolylchloride hydrochloride (6.58g, 0.040mol) and an added NaOH pellet (3.20g, 0.080mol). After 5days of stirring at rt, the product was extracted with dichloromethane. The reaction solution was dried over MgSO4, then the filtrate solvent was removed under reduced pressure to give a brown oil (4.01g, 75.0

According to the analysis of related databases, 6959-47-3, the application of this compound in the production field has become more and more popular.

Reference:
Article; Kim, Dongil; Kim, Sunghoon; Kim, Eunhee; Lee, Ha-Jin; Lee, Hyosun; Polyhedron; vol. 63; (2013); p. 139 – 146;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem