Adding a certain compound to certain chemical reactions, such as: 6221-01-8, Pyridine-2,5-dicarbaldehyde, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Quality Control of Pyridine-2,5-dicarbaldehyde, blongs to pyridine-derivatives compound. Quality Control of Pyridine-2,5-dicarbaldehyde
General procedure: To a solution of 2,5-dicarbaldehyde pyridine (50 mg), in 1,2-dichloroethane (3.6 mL), was added the aniline derivative (6 eq) and acetic acid (2 eq) were added. After stirring for 5 min at room temperature, the solution was treated with sodium triacetoxyborohydride (3 eq). It was then stirred at room temperature overnight and purified via preparative thin layer chromatography.
The synthetic route of 6221-01-8 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Virani, Saniya; Liang, Zhongxing; Yoon, Younghyoun; Shim, Hyunsuk; Mooring, Suazette R.; Bioorganic and Medicinal Chemistry Letters; vol. 29; 2; (2019); p. 220 – 224;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem