Related Products of 114-33-0 , The common heterocyclic compound, 114-33-0, name is N-Methylnicotinamide, molecular formula is C7H8N2O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: Complex 11 was prepared by the reaction of an acetonitrile solution of copper(II) acetate monohydrate (1mmol, 0.20g) with N-methylnicotinamide (2mmol, 0.27g) followed by addition of 2,5-dichlorobenzoic acid (2mmol, 0.38g). The reaction mixture was stirred until a blue product was precipitated (1day). The fine blue microcrystals were filtered off, washed with a small portion of water and dried at ambient temperature. The mother liquors obtained from filtration were left to crystallize. The blue crystals suitable for X-ray structure determination were separated after several days. Yield: 0.67g (85%).
The synthetic route of 114-33-0 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Hala?ka, Jozef; Lokaj, Jan; Jomova, Klaudia; R??i?kova, Zde?ka; Mazur, Milan; Moncol, Jan; Polyhedron; vol. 175; (2020);,
Pyridine – Wikipedia,
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