The origin of a common compound about 68325-15-5

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Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 68325-15-5, name is 3-Chloro-4-cyanopyridine. This compound has unique chemical properties. The synthetic route is as follows. Application In Synthesis of 3-Chloro-4-cyanopyridine

3-EthoxyisonicotinonitrileSodium ethoxide (53 mg, 0.74 mmol) was added to a 0C solution of 3-chloro-4-cyanopyridine (100 mg, 0.72 mmol) in DMF (1 mL). The mixture was stirred at 0C for 30 mm and at rt for 2h, then the mixture was concentrated in vacuo. To the residue Et20 was added, and the salts were filtered off. The filtrate was concentrated in vacuo to yield the title compound as a white solid. LC-MSA: tR= 0.67 mm; [M(35Cl)+H]= 149.06.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 68325-15-5, 3-Chloro-4-cyanopyridine.

Reference:
Patent; ACTELION PHARMACEUTICALS LTD; BOLLI, Martin; BOSS, Christoph; BROTSCHI, Christine; HEIDMANN, Bibia; SIFFERLEN, Thierry; WILLIAMS, Jodi T.; WO2014/141065; (2014); A1;,
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