Reference of 1824-81-3, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 1824-81-3, name is 2-Amino-6-picoline. A new synthetic method of this compound is introduced below.
2. Dissolve 10.80 g of 2-amino-6-methylpyridine (Compound 9) in 500 mL of acetonitrile, add 33.7 g of N-iodosuccinimide, and react at room temperature for 3 h. The precipitate was filtered, washed with 200 mL of cold acetonitrile, and dried under vacuum to obtain 12.2 g (compound 10) as an off-white solid with a yield of about 52%.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,1824-81-3, 2-Amino-6-picoline, and friends who are interested can also refer to it.
Reference:
Patent; China Agricultural University; Wang Zhanhui; Shen Jianzhong; Wen Kai; Li Chenglong; Yu Xuezhi; Zhang Suxia; Shi Weimin; Yu Wenbo; (19 pag.)CN110713457; (2020); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem