Application of 1018678-39-1, Adding some certain compound to certain chemical reactions, such as: 1018678-39-1, name is 4-Chloro-2-(trifluoromethyl)nicotinic acid,molecular formula is C7H3ClF3NO2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1018678-39-1.
A mixture of 4-chloro-2-(trifluoromethyl)nicotinic acid (1 .5 g, 6.65 mmol) in thionyl chloride (10.0 ml.) was stirred at 100C for 5 h. The reaction mixture was concentrated invacuo to afford the title compound (1 .60 g, Crude) Rf = 0.9 (5 % methanol in Dichloromethane).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1018678-39-1, 4-Chloro-2-(trifluoromethyl)nicotinic acid, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; NOVARTIS AG; JIRICEK, Jan; NG, Shuyi Pearly; RAO, Srinivasa P S; (126 pag.)WO2019/244049; (2019); A1;,
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