Adding a certain compound to certain chemical reactions, such as: 58530-53-3, 2,4-Dibromopyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 58530-53-3, blongs to pyridine-derivatives compound. SDS of cas: 58530-53-3
Preparation 742-Bromo-4-pyrrolidin-1-ylpyridine2,4-Dibromopyridine (300mg, 0.94mmol) and pyrrolidine (335mg, 4.7mmol) were combined in ethanol and heated at 700C overnight. The reaction mixture was concentrated in vacuo and the residue purified by column chromatography using an ISCO silica cartridge eluting with 0- 70% ethyl acetate: pentane. (208mg, 0.91 mmol, 97%).1H-NMR (CDCI3, 400MHz): delta 2.0 (m, 4H), 3.3 (m, 4H), 6.3 (m, 1 H), 6.6 (s, 1 H)1 7.9 (d, 1 H). LRMS m/z (APCI) 227 [MH]+.
The synthetic route of 58530-53-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; PFIZER LIMITED; WO2007/57775; (2007); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem