Reference of 63071-09-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 63071-09-0, name is 2-Hydroxymethyl-3-methylpyridine. This compound has unique chemical properties. The synthetic route is as follows.
General procedure: Hydroxy-methylpyridine 3b, 7, or 13, 1.9 mmol, was dissolved in 25 mL of 1,2-dichloroethane, 1.65 g (19 mmol) of activated manganese dioxide was added, and the mix-ture was stirred for 6 h at 50C. The precipitate was filtered off, the filtrate was evaporated under reduced pressure, and the residue was used in the next step without additional purification. 3-Methylpyridine-2-carbaldehyde (1c). Yield 185 mg (1.52 mmol, 80%), light oily material. 1 H NMR spectrum (CDCl 3 ), delta, ppm: 2.66 s (3H, Me), 7.39 d.d (1H, 5-H, J = 7.8, 4.6 Hz), 7.62 d (1H, 4-H, J = 7.8 Hz), 8.66 d (1H, 6-H, J = 4.6 Hz), 10.20 s (1H, CHO). Mass spectrum, m/z 122.06 (I rel 100%) [M + H] + . Calculated: M 122.06.
According to the analysis of related databases, 63071-09-0, the application of this compound in the production field has become more and more popular.
Reference:
Article; Krinochkin; Kopchuk; Chepchugov; Kovalev; Zyryanov; Rusinov; Chupakhin; Russian Journal of Organic Chemistry; vol. 53; 7; (2017); p. 963 – 970; Zh. Org. Khim.; vol. 53; 7; (2017); p. 951 – 958,8;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem