Related Products of 53014-84-9 ,Some common heterocyclic compound, 53014-84-9, molecular formula is C7H7NO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
A. Alpha-amino-alpha-(6-methyl-3-pyridinyl)acetonitrile To a solution of potassium cyanide (6.96 g, 107 mmol) and ammonium chloride (5.72 g, 107 mmol) in water (5 ml) was added 6-methyl-3-pyridin-carboxaldehyde (8.68 g, 71.5 mmol) and the reaction mixture was stirred at room temperature for 18 h. The reaction mixture was basified with 50% NaOH and extracted with ethyl acetate. The organic phase was dried (MgSO4) and evaporated to give the crude desired product in 7 g yield. The product was used without further purification.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 53014-84-9, 2-Methyl-5-formylpyridine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Novo Nordisk A/S; US5328923; (1994); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem